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Index > Protein center > Ccl3(Gene name) > Mouse
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  • Ccl3 (Gene name),
  • C-C motif chemokine 3 (Protein name ),  CCL3_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Ccl3(Mip1a;Scya3);
    Protein name:
    C-C motif chemokine 3;
    Alternative:
    L2G25B;Heparin-binding chemotaxis protein;SIS-alpha;Macrophage inflammatory protein 1-alpha(MIP-1-alpha);TY-5;Small-inducible cytokine A3;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Monokine with inflammatory, pyrogenic and chemokinetic properties. Has a potent chemotactic activity for eosinophils. Binding to a high-affinity receptor activates calcium release in neutrophils.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    92
    Sequence:
    50:
    MKVSTTALAV | LLCTMTLCNQ | VFSAPYGADT | PTACCFSYSR | KIPRQFIVDY | 
    92:
    FETSSLCSQP | GVIFLTKRNR | QICADSKETW | VQEYITDLEL | NA
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    SMR:
    UniGene:
    String:
    Pfam:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse C-C motif chemokine 3
    Cat.:
    E0092h
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Mouse C-C motif chemokine 3
    Cat.:
    E0092r
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    Packing:
    96T
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    ELISA Kit for Mouse C-C motif chemokine 3
    Cat.:
    E0092m
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    96T
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    ELISA Kit for Mouse C-C motif chemokine 3
    Cat.:
    E0092b
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Mouse C-C motif chemokine 3
    Cat.:
    E0092d
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Mouse C-C motif chemokine 3
    Cat.:
    U0092m
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse C-C motif chemokine 3
    Cat.:
    U0092b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse C-C motif chemokine 3
    Cat.:
    U0092d
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse C-C motif chemokine 3
    Cat.:
    U0092r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse C-C motif chemokine 3
    Cat.:
    U0092h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    Polyclonal Antibody for Mouse C-C motif chemokine 3
    Cat.:
    P0092Rb-m
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse C-C motif chemokine 3
    Cat.:
    P0092Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse C-C motif chemokine 3
    Polyclonal Antibody for Mouse C-C motif chemokine 3
    Cat.:
    P0092Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse C-C motif chemokine 3
    Monoclonal Antibody for Mouse C-C motif chemokine 3
    Monoclonal Antibody for Mouse C-C motif chemokine 3
    Monoclonal Antibody for Mouse C-C motif chemokine 3
    Monoclonal Antibody for Mouse C-C motif chemokine 3
    Monoclonal Antibody for Mouse C-C motif chemokine 3
    Protein for Mouse C-C motif chemokine 3
    Protein for Mouse C-C motif chemokine 3
    Protein for Mouse C-C motif chemokine 3
    Protein for Mouse C-C motif chemokine 3
    Protein for Mouse C-C motif chemokine 3

    R&D Technical Data

              12% SDS-PAGE Analysis

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    Precision

    Intra-assay Precision (Precision within an assay):Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.

    Intra-Assay CV: ≤ 5.4%

    Inter-assay Precision (Precision between assays):Three samples of known concentration were tested in five separate assays to assess inter-assay precision.

    Inter-Assay CV: ≤ 7.8%

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    Recovery

    Recovery was determined by spiking various levels of ACE into serum and plasma .

    Sample Type

    Average(%)

    Recovery Range(%)

    Serum

    99

    93-108

    Plasma

    99

    94-107

     

     

     

     

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    Linearity

     

    The linearity of the kit was assayed by testing samples spiked with appropriate concentration of ACE and their serial dilutions. The results were demonstrated by the percentage of calculated concentration to the expected.  

    Sample

    1:2

    1:4

    1:8

    1:16

    serum(n=5)

    90-99%

    91-102%

    95-103%

    96-107%

    EDTA plasma(n=5)

    91-97%

    95-101%

    94-102%

    93-106%

    heparin plasma(n=5)

    93-104%

     

    94-107%

    101-108%

    95-110%

     

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    References
    1. 1.
      "Cloning and characterization of a cDNA for murine macrophage inflammatory protein (MIP), a novel monokine with inflammatory and chemokinetic properties."
      Davatelis G. , Tekamp-Olson P. , Wolpe S.D. , Hermsen K. , Luedke C. , Gallegos C. , Coit D. , Merryweather J. , Cerami A.
      J. Exp. Med.167:1939-1944(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE
    2. 2.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ERRATUM;SEQUENCE REVISION
    3. 3.
      "A family of small inducible proteins secreted by leukocytes are members of a new superfamily that includes leukocyte and fibroblast-derived inflammatory agents, growth factors, and indicators of various activation processes."
      Brown K.D. , Zurawski S.M. , Mosmann T.R. , Zurawski G.
      J. Immunol.142:679-687(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    4. 4.
      "Sequence of the murine haemopoietic stem cell inhibitor/macrophage inflammatory protein 1 alpha gene."
      Grove M. , Lowe S. , Graham G. , Pragnell I. , Plumb M.
      Nucleic Acids Res.18:5561-5561(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
      strain: DBA/2J.
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    6. 6.
      "Genomic structure of murine macrophage inflammatory protein-1 alpha and conservation of potential regulatory sequences with a human homolog, LD78."
      Widmer U. , Yang Z. , van Deventer S. , Manogue K.R. , Sherry B. , Cerami A.
      J. Immunol.146:4031-4040(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE
    7. 7.
      "Sequence polymorphisms in the chemokines Scya1 (TCA-3), Scya2 (monocyte chemoattractant protein (MCP)-1), and Scya12 (MCP-5) are candidates for eae7, a locus controlling susceptibility to monophasic remitting/nonrelapsing experimental allergic encephalomyelitis."
      Teuscher C. , Butterfield R.J. , Ma R.Z. , Zachary J.F. , Doerge R.W. , Blankenhorn E.P.
      J. Immunol.163:2262-2266(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE
      strain: B10.S/J.
      strain: BALB/cJ.
      strain: DBA/2J.
      strain: NOD/LtJ.
      strain: SJL/J.
      tissue: Spleen.
    8. 8.
      "Macrophages secrete a novel heparin-binding protein with inflammatory and neutrophil chemokinetic properties."
      Wolpe S.D. , Davatelis G. , Sherry B. , Beutler B. , Hesse D.G. , Nguyen H.T. , Moldawer L.L. , Nathan C.F. , Lowry S.F. , Cerami A.
      J. Exp. Med.167:570-581(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 24-42
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